Cyclo(-Arg-Gly-Asp-D-Phe-Lys) Trifluoroacetate

Supplier: BACHEM AMERICAS INC

4069635.0001 4069635.0005
H-7326.0001BAEA 193.17 CAD
H-7326.0001BA H-7326.0005BA
Cyclo(-Arg-Gly-Asp-D-Phe-Lys) Trifluoroacetate
Proteins and Peptides

An RGD tumor-targeting peptide, which binds to αvβ3 receptors. c(RGDfK) can be easily conjugated to fluorophore tags, chelators, or carriers. Palecek et al. converted the ε-amino group into the azide by diazo transfer allowing further functionalization by click chemistry. Mercapto groups can be introduced via acylation of c(RGDfK) with S-acetylthioacetic acid (SATA).

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