Anti-CDKN1A Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Supplier: Bioss

BS-5238R-FITC

10411-106EA 1320.03 CAD

10411-106

Anti-CDKN1A Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Antibodies

May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: CDKN1A
Clonality: Polyclonal
Clone: 0
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity:

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