Anti-EPHA10 Rabbit Polyclonal Antibody

Supplier: Prosci

Western blot analysis of EphA10 in 293 cell lysate with EphA10 antibody at (A) 1 ug/mL and (B) 2 ug/mL.

Western blot analysis of EphA10 in 293 cell lysate with EphA10 antibody at (A) 1 ug/mL and (B) 2 ug/mL.

5253_S

10750-586EA 301.81 CAD

10750-586

Anti-EPHA10 Rabbit Polyclonal Antibody

Antibodies

EphA10 Antibody: Eph receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility of neuronal and endothelial cells in central nervous system function and in development. Eph receptors can be divided into two subgroups: EphA and EphB. In mammals, the EphA class consists of eight members (EphA 1-7 and 10) that in general bind to ephrin-A members linked to the cell membrane through a glycosylphosphatidylinositol linkage. The EphB class consists of six members (EphB 1-6) that in general bind ephrin-B members that transverse the cell membrane. The Ephrin / EPH signaling pathway networks with the WNT signaling pathway during embryogenesis, tissue regeneration, and carcinogenesis. Recent studies show that Eph/EFN might be relevant in normal B-cell biology and could represent new potential prognostic markers and therapeutic targets for CLL.

Type: Primary
Antigen: EPHA10
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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