Human Recombinant IL16 (from E. coli)

Supplier: Prosci

40-261 40-262
10072-070EA 481.9 CAD
10072-070 10072-072
Human Recombinant IL16 (from E. coli)
Proteins and Peptides

IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and murine IL-16 show significant cross-species reactivity. Recombinant human IL-16 is a 13.5 kDa protein consisting of 130 amino acid residues.


Store in working aliquots at -20°C. Avoid freeze/thaw cycles.

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SPECIFICATIONS

Protein/peptide name IL16 IL16
Environmentally Preferable
Protein synonyms NIL16|Lymphocyte chemoattractant factor|prIL-16|IL-16|PRIL16|Pro-interleukin-16|LCF NIL16|Lymphocyte chemoattractant factor|prIL-16|IL-16|PRIL16|Pro-interleukin-16|LCF
Protein/peptide type Recombinant Recombinant
Species Human Human
Source E. coli E. coli
Biological activity Biological activity was determined by its ability to chemoattract human CD4+ T lymphocytes using a concentration range of 1.0 - 100.0 ng/mL. Biological activity was determined by its ability ot chemoattract human CD4+ T - Lymphocytes using a concentration range of 50.0 - 100.0 ng/mL.
Purity >98% >98%
Formulation Lyophilized Lyophilized

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