Mouse Recombinant NGF beta (from E. coli)

Supplier: Prosci

40-495 40-505
10072-224EA 481.9 CAD
10072-224 10072-240
Mouse Recombinant NGF beta (from E. coli)
Proteins and Peptides

Beta-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Beta-NGF is a potent neurotrophic factor that signals through its receptor beta-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Beta-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of human beta-NGF is a noncovalently disulfide-linked homodimer, of two 13.5 kDa polypeptide monomers (238 total amino acid residues). The three disulfide bonds are required for biological activity. The functional form of murine beta-NGF is a noncovalently disulfide-linked homodimer, of two 13.4 kDa polypeptide monomers (240 total amino acid residues). The three disulfide bonds are required for biological activity.


Store in working aliquots at -20°C. Avoid freeze/thaw cycles.

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