Rat Recombinant IL6 (from E. coli)

Supplier: Prosci

40-112 40-249 40-523 40-466

10072-024EA 481.9 CAD

10072-024 10072-064 10072-220 10072-482

Rat Recombinant IL6 (from E. coli)

Proteins and Peptides

IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues. Recombinant rat IL-6 is a 21.7 kDa protein containing 187 amino acid residues. Recombinant murine IL-6 is a 21.7 kDa protein containing 187 amino acid residues.

Recombinant murine IL-6 is a 21.7 kDa protein containing 187 amino acid residues.

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