Mouse Recombinant Granzyme B (from Baculovirus (Insect cells))

Supplier: ProSci
40-125
10072-640EA 492.19 CAD
10072-640
Mouse Recombinant Granzyme B (from Baculovirus (Insect cells))
Proteins and Peptides
Granzyme B is a cysteine protease found in the cytoplasmic granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme B is required for the induction of target cell lysis, which occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms. Proteolytic cleavage of substrates by Granzyme B takes place primarily after aspartic acid residues. Recombinant murine Granzyme B is a glycosylated 227 amino acid protein, comprising the mature active portion of the murine Granzyme B precursor. The apparent molecular weight is 28.9 kDa by mass spectrometry.

Store in working aliquots at -20°C. Avoid freeze/thaw cycles.
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