Mouse Recombinant Resistin (from E. coli)

Supplier: Prosci

40-483 40-488 40-325

10072-516EA 481.9 CAD

10072-516 10072-520 10072-944

Mouse Recombinant Resistin (from E. coli)

Proteins and Peptides

Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM-α and RELM-β share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Recombinant human Resistin is a 19.5 kDa disulfide-linked homodimeric protein composed of two identical 92 amino acid chains linked by a single disulfide bond. Recombinant murine Resistin is a 20.2 kDa disulfide-linked homodimeric protein composed of two identical 94 amino acid chains linked by a single disulfide bond. Recombinant rat Resistin is a 20.0 kDa disulfide-linked homodimeric protein composed of two 94 identical amino acid chains linked by a single disulfide bond.

Store in working aliquots at -20°C. Avoid freeze/thaw cycles.

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