JC-10 ≥95% (by HPLC), Ultrapure

Supplier: Enzo Life Sciences

JC-10 ≥95% (by HPLC), Ultrapure

JC-10 ≥95% (by HPLC), Ultrapure

Synonyms: Enhanced JC-1

ENZ-52305

89166-016EA 432 CAD

89166-016

JC-10 ≥95% (by HPLC), Ultrapure

JC-10

Mitochondria dye

JC-10 is a derivative of JC-1 useful for determining mitochondrial membrane potential by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. JC-10 accumulates in mitochondria, selectively generating an orange J-aggregate emission profile (590 nm) in healthy cells. However, upon cell injury, as membrane potential decreases, JC-10 monomers are generated, resulting in a shift to green emission (525 nm). The principal advantages of JC-10 relative to JC-1 include improved solubility in aqueous media and an ability to detect subtler changes in mitochondrial membrane potential loss. JC-10 allows for both qualitative visualization, considering the shift from orange to green fluorescence emission, and quantitative detection, considering the fluorescence intensity ratio, of mitochondrial membrane potential changes. Wavelength Maxima: Excitation 510nm, Emission 525nm

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