Anti-POMP Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences
PW9715-0025 PW9715-0100
89162-420EA 353.92 CAD
89162-420 89162-422
Anti-POMP Rabbit Polyclonal Antibody
Antibodies
The assembly of individual mammalian proteasome subunits into catalytically active 20S proteasome is a complex process, with biogenesis of the mammalian 20S proteasome occuring via precursor complexes containing α and unprocessed β subunits. The pro-peptides of the β subunits are thought to prevent premature conversion of the precursor complexes into matured particles and are needed for efficient β subunit incorporation. The complex biogenesis is tightly regulated, requiring additional components such as the maturation factor POMP (proteasome maturation protein), an ubiquitous protein in eukaryotic cells. Mammalian POMP is functionally related to but not interchangable with its yeast homologue Ump1. POMP is associated purely with the precursor intermediates and is degraded upon final maturation. Northern blot experiments have revealed that expression of POMP is induced after treatment with interferon γ.

  • For Immunohistochemistry, Immunoprecipitation, Western Blot

Recognizes human, rat and monkey POMP/Ump1.

Type: Primary
Antigen: POMP
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human
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