RK-682 ≥98% (by HPLC)

Supplier: Enzo Life Sciences

BML-PR112-0200 BML-PR112-1000
89161-780EA 244.9 CAD
89161-780 89161-782
RK-682 ≥98% (by HPLC)
RK-682

RK-682 is a novel tyrosine phosphatase inhibitor isolated from Streptomyces sp. It inhibits the dual specificity VHR phosphatase (IC50=2.0µM) selectively over CD45 (IC50=54µM), Cdc25B and PTP1B (IC50~42µM). RK-682 inhibits cell cycle progression of Ball-1 cells at the G1/S transition and enhances ATP-induced long-term potentiation in guinea pig hippocampal CA1 neurons. Shows potent activity against HIV-1 protease.


  • VHR inhibitor


Pale yellow solid.


Soluble in DMSO (25mg/ml), 100% ethanol (10mg/ml), methanol or dimethyl formamide.

Formula: C₂₁H₃₆O₅
MW: 368.5 g/mol
Storage Temperature: Freezer
CAS Number: 154639-24-4
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