Calpeptin ≥98% (by TLC)
Supplier: Enzo Life Sciences
Synonyms:
Benzyl ((S)-4-methyl-1-oxo-1-(((S)-1-oxohexan-2-yl)amino)pentan-2-yl)carbamate
, benzyl N-[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxohexan-2-yl]amino]pentan-2-yl]carbamate
, Cbz-Leu-Nle-al
Calpain and cathepsin inhibitor
Membrane permeable inhibitor of calpain I and II, cathepsin L and cathepsin K (IC50=0.11 nM). Promotes neurite elongation in differentiating PC12 cells. Prevents Ca2+-ionophore induced degradation of actin binding protein and P235 in platelets. Inhibits myosin light chain phosphorylation in platelets stimulated by collagen, ionomycin (Prod. No. ALX-450-006) or thrombin. Inhibits LPS induced iNOS transcription and NF-kappaB activation, possibly via proteasome inhibition.
Formula:
C₂₀H₃₀N₂O₄ MW: 362.47 g/mol |
MDL Number:
MFCD00155623 CAS Number: 117591-20-5 |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...