Mirin ≥95% (by TLC)
Supplier: Enzo Life Sciences
BML-GR357-0005
BML-GR357-0025
89158-992EA
170.64
CAD
89158-992
89158-994
Mirin ≥95% (by TLC)
Mirin
MRN inhibitor
The MRN-ATM pathway is essential for sensing the signaling from DNA double-strand breaks. Mirin is an inhibitor of MRN discovered using a forward chemical genetic screen. It prevents MRN-dependent activation of ATM without affecting ATM protein kinase activity and it inhibits Mre11-associated exonuclease activity. IC50=66µM. It abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells.
Formula:
C₁₀H₈N₂O₂S |
MDL Number:
MFCD05885480 CAS Number: 299953-00-7 |
|
Learn more

About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...