6-ECDCA ≥97% (by TLC)

Supplier: Enzo Life Sciences

Synonyms: Obeticholic acid, (R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid, INT-747

BML-GR246-0005 BML-GR246-0025
89158-846EA 197.5 CAD
89158-846 89158-848
6-ECDCA ≥97% (by TLC)
6-ECDCA

FXR ligand


A novel derivative of cholic acid which acts as a potent and selective FXR agonist (EC50= 99nM) displaying anticholeretic activity in an in vivo rat model of cholestasis. It not only inhibits vascular smooth muscle cell inflammation and migration but also promotes adipocyte differentiation and regulates adipose cell function in vivo.

Formula: C₂₆H₄₄O₄
MW: 420.63 g/mol
MDL Number: MFCD16621104
CAS Number: 459789-99-2
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