6-ECDCA ≥97% (by TLC)
Supplier: Enzo Life Sciences
Synonyms:
Obeticholic acid, (R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid, INT-747
FXR ligand
A novel derivative of cholic acid which acts as a potent and selective FXR agonist (EC50= 99nM) displaying anticholeretic activity in an in vivo rat model of cholestasis. It not only inhibits vascular smooth muscle cell inflammation and migration but also promotes adipocyte differentiation and regulates adipose cell function in vivo.
Formula:
C₂₆H₄₄O₄ MW: 420.63 g/mol |
MDL Number:
MFCD16621104 CAS Number: 459789-99-2 |
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