Mevastatin ≥95%

Supplier: Enzo Life Sciences

Mevastatin ≥95%

Mevastatin ≥95%

Synonyms: (1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate , Compactin

BML-G233-0010 BML-G233-0050

89158-584EA 151 CAD

89158-584 89158-586

Mevastatin ≥95%

Mevastatin

HMG-CoA reductase inhibitor

Mevastatin inhibits isoprenoid biosynthesis by inhibition of HMG-CoA reductase (Ki for acid form is 1 nM) and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. It causes cells to arrest early in the G1 phase. Mevastatin is a close structural analog of lovastatin and both agents have the same biochemical and pharmacological activities. Mevastatin is inactive in cell-free assays. In cells however, it is hydrolyzed to the active free acid form by intracellular esterases.

Formula: C₂₃H₃₄O₅
MW: 390.52 g/mol

MDL Number: MFCD05662341
CAS Number: 73573-88-3

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