SB-3CT ≥98% (by TLC)
Supplier: Enzo Life Sciences
Synonyms:
2-(((4-Phenoxyphenyl)sulphonyl)methyl)thiirane, 2-(((4-Phenoxyphenyl)sulfonyl)methyl)thiirane
Competitive, mechanism-based inhibitor of matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9). It possesses Ki values in the nanomolar range against the gelatinases (14nM for MMP-2; 600nM for MMP-9), but in the micromolar range against other metalloproteinases (206µM for MMP-1, 15µM for MMP-3, 96µM for MMP-7, and 4µM for ADAM17/TACE). This inhibitor has also been used in vitro, in vivo, and in tissue culture. In vivo, it is metabolized to an even more potent gelatinase inhibitor.
- MMP inhibitor
White solid.
Soluble in DMSO (at least 30mM) or 100% ethanol.
Formula:
C₁₅H₁₄O₃S₂ MW: 306.4 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD09836266 CAS Number: 292605-14-2 |
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