(±)-Blebbistatin ≥98%
Supplier: Enzo Life Sciences
Synonyms:
3a-Hydroxy-6-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one, Blebbistatin
Inhibitor of non-muscle myosin II
Blebbistatin (so named because of its ability to block cell blebbing) is a selective and high-affinity (IC50 approx. 4 µM) inhibitor of non-muscle myosin II. During cell division blebbistatin inhibits contraction of the cleavage furrow without disrupting mitosis. It inhibits pancreatic adenocarcinoma cellular invasiveness and PDGF-stimulated fibroblast-collagen matrix contraction.
Formula:
C₁₈H₁₆N₂O₂ MW: 292.33 g/mol |
MDL Number:
MFCD04113775 CAS Number: 674289-55-5 |
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