HNMPA-(AM)3 ≥98% (by TLC)

Supplier: Enzo Life Sciences

Synonyms: Hydroxy-2-naphthalenylmethylphosphonic acid tri-acetoxymethyl ester

BML-EI248-0005 BML-EI248-0025

89157-866EA 267.02 CAD

89157-866 89157-868

HNMPA-(AM)3 ≥98% (by TLC)

HNMPA-(AM)3

HNMPA-(AM)3 is a cell-permeable analog of HNMPA. It inhibits insulin receptor tyrosine kinase activity (IC50=100 µM) and insulin-stimulated glucose oxidation in isolated rat adipocytes (IC50=10 µM). It has no effect on PKA (at concs. up to 1 mM) or PKC (at concs. up to 420 µM). Inhibits both serine and tyrosine autophosphorylation by the human insulin receptor. Does not affect protein kinase C (PKC) or cAMP-dependent protein kinase (PKA).

Insulin receptor inhibitor

Colorless oil.

Soluble in DMSO (>20mg/ml) or 100% ethanol (>20mg/ml).

Formula: C₂₀H₂₃O₁₀P
MW: 454.4 g/mol
Storage Temperature: Freezer

CAS Number: 120944-03-8

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