GYY 4137 ≥95%

Supplier: Enzo Life Sciences

430-163-M010 430-163-M050
89151-288EA 121.66 CAD
89151-288 89151-290
GYY 4137 ≥95%
GYY 4137

H2S donor


Water-soluble, slow-releasing hydrogen sulfide (H2S) donor. Shows vasodilator and antihypertensive activity in rats in both acute (L-NAME-induced) or chronic (spontaneously hypertensive) hypertension models. Inhibits LPS-induced release of various proinflammatory mediators (such as IL-1β, IL-6, TNF-α, nitric oxide (NO) and PGE2) in RAW264.7 cells. Increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-κB, ATF-2 and HSP27 dependent pathways in RAW264.7 cells.


Synthetic.

Formula: C₁₁H₁₆NO₂PS₂·C₄H₉NO
CAS Number: 106740-09-4
https://digitalassets.avantorsciences.com/adaptivemedia/rendition?id=0c7ba5cf5340e7228a5e1328972f44f81010c26e&vid=8ea09abd019640a0c2a300383f36a5b8fc8dfa49&prid=web&clid=SAPDAM

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