A77 1726 ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Synonyms:
2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide, (E/Z)-Teriflunomide
Dihydrorotate dehydrogenase inhibitor
Physiologically active metabolite of the immunosuppressive drug leflunomide (Prod. No. ALX-430-095). Inhibits the activity of dihydrorotate dehydrogenase and of protein tyrosine kinases. Blocks TNF-mediated NF-kappaB activation in a dose- and time-dependent manner. Also inhibits the activity of cyclooxygenase-2 (COX-2) in vitro and in vivo.
Formula:
C₁₂H₉F₃N₂O₂ MW: 270.211 g/mol |
MDL Number:
MFCD00910058 CAS Number: 108605-62-5 |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...