Genistein (synthetic) ≥99% (by HPLC)

Supplier: Enzo Life Sciences

Synonyms: 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, 4',6'-Dihydroxy-3-(4-hydroxyphenyl)benzo(e)oxacyclohex-2-en-4-on, 5,7-Dihydroxy-3-(4-hydroxyphenyl)chromen-4-one, 4',5,7-Trihydroxyisoflavone

350-006-G001 350-006-M010 350-006-M025 350-006-M050 350-006-M100
89148-896EA 1248.2 CAD
89148-896 89148-898 89148-900 89148-902 89148-904
Genistein (synthetic) ≥99% (by HPLC)
Genistein

Tyrosine kinase inhibitor


Tyrosine protein kinase inhibitor. Inhibits phosphorylation of EGFR kinase. Inhibits tumor cell proliferation and induces tumor cell differentiation. Inhibits topoisomerase II activity in vivo. Produces cell cycle arrest and apoptosis. Potent inhibitor of α-glucosidase, IC50 = 50nM.Direct inhibitor of insulin-induced glucose uptake in adipocytes (IC50=20µM).


Synthetic.

Formula: C₁₅H₁₀O₅
MW: 270.24 g/mol
MDL Number: MFCD00016952
CAS Number: 446-72-0
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