Dynasore ≥98% (by NMR)

Supplier: Enzo Life Sciences

Dynasore ≥98% (by NMR)

Dynasore ≥98% (by NMR)

Synonyms: N'-(3,4-Dihydroxybenzylidene)-3-hydroxy-2-naphthohydrazide, 3-Hydroxynaphthalene-2-carboxylic acid (3,4-Dihydroxybenzylidene)hydrazide

270-502-M005 270-502-M025

89148-114EA 109.02 CAD

89148-114 89148-116

Dynasore ≥98% (by NMR)

Dynasore

GTPase inhibitor

Small molecule GTPase inhibitor targeting Dynamin-1, Dynamin-2 and Drp1 (mitochondrial Dynamin). Noncompetitive inhibitor of Dynamin GTPase activity. Blocks Dynamin-dependent endocytosis in cells (including neurons). Fast acting (seconds). Strong, dose dependent block of the traffic and accumulation of transferrin with 80µM dynasore (IC50 = 15µM). Has also been shown to block human papillomavirus type 16 (HPV16) and bovine papillomavirus type 1 (BPV1) (pseudovirions) infections.

Formula: C₁₈H₁₄N₂O₄

MDL Number: MFCD00292551
CAS Number: 304448-55-3

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