PI103 ≥97% (by HPLC)

Supplier: Enzo Life Sciences

PI103 ≥97% (by HPLC)

PI103 ≥97% (by HPLC)

Synonyms: PI-103, mTOR Inhibitor V, PI 3-K Inhibitor V, 3-(4-Morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol

270-460-M001 270-460-M005

89147-964EA 93.22 CAD

89147-964 89147-966

PI103 ≥97% (by HPLC)

PI103

Potent, cell permeable and ATP-competitive inhibitor of DNA-PK, phosphoinositide 3-kinase (PI(3)K), the rapamycin-sensitive (mTORC1) and rapamycin-insensitive (mTORC2) complexes of the protein kinase mTOR. Exhibits little activity towards a panel of more than 40 other kinases even at concentrations as high as 10µM. Effectively blocks cell proliferation in glioma cell lines both in vitro and in vivo.

Inhibitor of DNA-PK, PI3 kinase and mTOR

Off-white solid.

Soluble in DMSO (5mg/ml; warm).

Formula: C₁₉H₁₆N₄O₃
MW: 348.36 g/mol
Storage Temperature: Freezer

MDL Number: MFCD11983145
CAS Number: 371935-74-9

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