Compound E ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Synonyms: (S)-2-(2-(3,5-Difluorophenyl)acetamido)-N-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanamide

270-415-M001 270-415-C250
89147-838EA 251.99 CAD
89147-838 89147-840
Compound E ≥98% (by HPLC)
Compound E

gamma-Secretase inhibitor


Cell permeable, potent, selective, non-transition state and non-competitive inhibitor of γ-secretase (IC50=0.3nM for total β-amyloid) and Notch processing. At higher concentrations (20-400µM), only weakly affects the presenilase activity. Activity tested!

Formula: C₂₇H₂₄F₂N₄O₃
MW: 490.511 g/mol
MDL Number: MFCD04974531
CAS Number: 209986-17-4
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