1400W dihydrochloride ≥98%
Supplier: Enzo Life Sciences
Synonyms:
1400W 2HCl, N-(3-(Aminomethyl)benzyl)acetimidamide dihydrochloride
iNOS inhibitor
A slow, tight binding and highly selective inhibitor of inducible nitric oxide synthase (iNOS/NOS II) in vitro and in vivo. Binds tightly to iNOS with a Kd of 7nM. In contrast, inhibition of nNOS and eNOS is weaker and rapidly reversible with Ki values of 2 and 50µM respectively. Inhibits tumor growth in vivo. Prevents circulatory failure but not organ injury induced by endotoxin. Displays protective effects in oxygen-deprived brain slices.
Formula:
C₁₀H₁₅N₃·2HCl MW: 250.167 g/mol |
MDL Number:
MFCD03428622 CAS Number: 214358-33-5 |
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