Pepstatin A

Supplier: Enzo Life Sciences

260-085-M005 260-085-M025 260-085-M100
89146-796EA 88.48 CAD
89146-796 89146-798 89146-800
Pepstatin A
Proteins and Peptides

Protease inhibitor


Inhibitor of aspartate (acid) proteases, including pepsin, cathepsin D, renin, chymosin, bacterial aspartic proteinases and HIV proteases. Efficiently inhibits Fcγ receptor induction by IFN-γ. Blocks the endocytic pathway followed by an antibody when it enters the cell at the level of early endosomal compartments, resulting in inhibition of autoantigen presentation or viral transmission. Suppresses p-53-dependent apoptosis in lymphoid cells as well as TNFα-induced apoptosis in U937 cells. Inhibits degradation of autophagic cargo inside autophagolysosomes.

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