EEDQ (ethyl-N-(2-ethoxy-1,2-dihydroquinoline)carboxylate)
Supplier: BACHEM AMERICAS INC
Synonyms:
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline, N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, Ethyl 2-ethoxyquinoline-1(2H)-carboxylate
Sequence: N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
EEDQ permits the coupling of acylamino acids with amino acid esters in high yield without concomitant racemization. In a study aiming at the optimization of the coupling of 3,5-dinitrobenzoyl-Leu to 3-aminopropyl-silica (Yang et al.) significant levels of racemization were observed with all the tested coupling reagents except for EEDQ .
Formula:
C₁₄H₁₇NO₃ MW: 247.29 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00006703 CAS Number: 16357-59-8 |
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