(4-((2-Methylphenyl)aminocarbonyl)-aminophenyl)acetyl-Fibronectin CS-1 Fragment (1980-1983), Bachem

Supplier: BACHEM AMERICAS INC

4029156.0005 4029156.0025
N-1765.0005BAEA 877.5 CAD
N-1765.0005BA N-1765.0025BA
(4-((2-Methylphenyl)aminocarbonyl)-aminophenyl)acetyl-Fibronectin CS-1 Fragment (1980-1983), Bachem
Proteins and Peptides

The VLA-4 inhibitor BIO-1211 based on the LDVP motif represents a selective, tight-binding inhibitor of integrin α₄β₁ achieved by appending an optimal organic group to the N-terminus of the peptide (Kd = 70 pM). Moreover, this inhibitor exhibited > 200-fold selectivity for the activated form of the integrin α₄β₁ receptor.

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