Tertiapin, Bachem

Supplier: BACHEM AMERICAS INC

4031297.0500 4031297.1000
N-1745.0500BAEA 1032.67 CAD
N-1745.0500BA N-1745.1000BA
Tertiapin, Bachem
Proteins and Peptides

Tertiapin (TPN), a potent inhibitor of the inward-rectifier K⁺ channels, blocked a G-protein-gated channel (GIRK1/4) and the ROMK1 channel with nanomolar affinities, however a closely related channel, IRK1, was insensitive to tertiapin. Thus, tertiapin will be a powerful ligand for purifying functional channels as well as for screening pharmaceutical agents against these channels.

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