Ac-Trp-Glu-His-Asp-aldehyde (pseudo acid)

Supplier: BACHEM AMERICAS INC

4027878.0005 4027878.0025
N-1630.0005BAEA 619.42 CAD
N-1630.0005BA N-1630.0025BA
Ac-Trp-Glu-His-Asp-aldehyde (pseudo acid)
Proteins and Peptides

See also the Asp derivatives N-1425 and N-1430, and Z-YVAD-FMK (N-1595).


Ac-WEHD-CHO, a very potent reversible inhibitor of caspase-1 (ICE). It bears the optimal tetrapeptide recognition motif for this enzyme. With a Ki of 56 pM it belongs to the most potent reversible, peptide-based inhibitors described for any protease. For caspase-8 a Ki of 21.1 nM has been reported.

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