Z-Phe-Tyr-Aldehyde
Supplier: BACHEM AMERICAS INC
4027130.0025
4027130.0100
N-1540.0025BAEA
476.5
CAD
N-1540.0025BA
N-1540.0100BA
Z-Phe-Tyr-Aldehyde
Proteins and Peptides
Please see also the inhibitors H-7650, N-1000, N-1040, N-1105, N-1125, N-1315, N-1320, N-1380, N-1395, and N-1855.
Z-Phe-Tyrosinal is a potent and selective cathepsin L inhibitor. In the pit formation assay with unfractionated rat bone cells, 1.5 nM of Z-FY-CHO markedly inhibited parathyroid hormone-stimulated osteoclastic bone resorption. In ovariectomized mice, it suppressed at 2.5-10 mg/kg/day ip for four weeks bone weight loss dose-dependently.
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