Human;Pig;Rat Glucagon (1-29)

Supplier: BACHEM AMERICAS INC

4033017.0001 4033017.0005
H-6790.0001BAEA 571.38 CAD
H-6790.0001BA H-6790.0005BA
Human;Pig;Rat Glucagon (1-29)
Proteins and Peptides

For the long-acting GLP-1 analog liraglutide see H-6724.


Glucagon is a 29 amino acid containing peptide hormone processed from proglucagon. As a counterregulatory hormone for insulin, glucagon plays a critical role in maintaining glucose homeostasis in vivo in both animals and humans. Not surprisingly, glucagon and glucagon receptor have been pursued extensively as potential targets for the therapeutic treatment of diabetes. As Aβ peptides and IAPP, glucacon tends to form gel-like fibrillar aggregates. These fibrils were found to be toxic through the activation of apoptotic signaling pathways. Hence the aggregation behavior of glucagon has been studied extensively.

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SPECIFICATIONS

Protein/peptide name Glucagon (1-29)
Environmentally Preferable
Species Pig,Human,Rat
Source
CAS No. 16941-32-5
MDL No. MFCD00167532
Sequence H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH
Molecular weight 3482.80
Molecular formula C₁₅₃H₂₂₅N₄₃O₄₉S
Storage conditions –20 ± 5 °C

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