(Pyr¹¹)-beta-Amyloid (11-40)

Supplier: BACHEM AMERICAS INC

4037661.0500 4037661.1000
H-6382.0500BAEA 503.75 CAD
H-6382.0500BA H-6382.1000BA
(Pyr¹¹)-beta-Amyloid (11-40)
Proteins and Peptides

pEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV, the N-terminally truncated isoform of the amyloid β-protein (Aβ) beginning with a pyroglutamate (Pyr) residue at position 11 was used in experiments studying the generality of fibrillogenesis-related helix formation. Comparing the fibrillogenesis kinetics of many of the most important clinically relevant amyloid β-protein alloforms it could be observed that among these peptides (Pyr¹¹)-amyloid β-protein (11-40) exhibited the greatest retardation of fibrillization rate.

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