Rat C-Peptide 1 Trifluoroacetate

Supplier: BACHEM AMERICAS INC

4045921.0500 4045921.1000
H-6136.0500BAEA 1032.67 CAD
H-6136.0500BA H-6136.1000BA
Rat C-Peptide 1 Trifluoroacetate
Proteins and Peptides

Synthesized prosequences from insulin.


Studies of the cellular effects of C-peptide have shown that it binds specifically in a nanomolar concentration range to a G-protein coupled membrane receptor, with subsequent activation of Ca²⁺-dependent intracellular signaling pathways. This resulted in stimulation of both Na⁺-K⁺-ATPase, and endothelial nitric oxide synthase activities. Administration of C-peptide to streptozotocin induced diabetic rats elicited a substantial increase in whole-body glucose turnover.

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