Bovine;Guinea pig;Human;Mouse;Rat GLP-1 (1-37) Trifluoroacetate

Supplier: BACHEM AMERICAS INC

4037542.0500 4037542.1000
H-5552.0500BAEA 794.35 CAD
H-5552.0500BA H-5552.1000BA
Bovine;Guinea pig;Human;Mouse;Rat GLP-1 (1-37) Trifluoroacetate
Proteins and Peptides

For the long-acting GLP-1 analog liraglutide see H-6724.


Glucagon-Like Peptide 1 (GLP-1) is synthesized by posttranslational processing of proglucagon in the intestine and pancreas and plays an important role in metabolic homeostasis. Among the different molecular forms, such as GLP-1 (7-36) amide and GLP-1 (7-37), the function of GLP-1 (1-37) has been unclear. GLP-1 (1-37) was shown to convert intestinal epithelial cells into insulin-producing cells. These observations turned GLP-1 (1-37) into a new promising therapeutic compound for the treatment of diabetes mellitus. In animal models of dilated cardiomyopathy, hypertensive heart failure, and myocardial infarction, GLP-1 has shown a remarkable cardioprotective activity.

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