Bovine;Human;Mouse;Rat (Pyr¹)-Apelin-13

Supplier: BACHEM AMERICAS INC

4029110.0001 4029110.0005
H-4568.0001BAEA 325.67 CAD
H-4568.0001BA H-4568.0005BA
Bovine;Human;Mouse;Rat (Pyr¹)-Apelin-13
Proteins and Peptides

The pyroglutamyl form of apelin-13 exhibited a high activity with an EC₅₀ value of 0.30 nM. pERPRLSHKGPMPF is probably the final product of the post-translational modification of apelin and the biologically active endogenous ligand. (Pyr¹)-Apelin-13 has been identified as the predominant apelin isoform in the human heart. Pyr-Apelin-13 stimulates glucose utilization in normal and obese insulin-resistant mice. It could be required for the maintenance of insulin sensitivity.

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