Bovine;Human;Mouse;Rat Apelin-13

Supplier: BACHEM AMERICAS INC

4029109.0001 4029109.0005
H-4566.0001BAEA 189.95 CAD
H-4566.0001BA H-4566.0005BA
Bovine;Human;Mouse;Rat Apelin-13
Proteins and Peptides

Apelin-13, generated from apelin-36, is an endogenous peptide ligand for the human APJ receptor, a putative receptor protein related to the angiotensin receptor (AT1). Apelin-13 exerted an acidification-rate-promoting activity in the CHO cells expressing the APJ receptor with a median effective concentration (EC₅₀) value of 0.37 nM. In a study of Valle et al. chronic central administration of apelin-13 over 10 days increased food intake, body weight, locomotor activity and body temperature in C57BL/6 mice.

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