H-Asp-Ala-His-Lys-OH, Bachem

Supplier: BACHEM AMERICAS INC

4009490.0100
H-2020.0100BAEA 1161.77 CAD
H-2020.0100BA
H-Asp-Ala-His-Lys-OH, Bachem
Proteins and Peptides

Short histidine-containing peptides can form stable complexes with copper and other transition metals. See also His-Leu (G-2310) and the product family 'Liver Cell Growth Factor (GHK) and Analogs'.


The tetrapeptide DAHK corresponding to the N-terminal sequence of human serum albumin forms a tight binding site for Cu(II) ions. DAHK inhibits Cu(II)-induced oxidative DNA double strand breaks. The tetrapeptide is as effective as HSA in preventing neuronal death induced by CuCl₂/ascorbic acid. DAHK may be an effective, small-molecular-weight alternative to HSA as a therapeutic agent for stroke.

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SPECIFICATIONS

Protein/peptide name H-Asp-Ala-His-Lys-OH
Environmentally Preferable
Protein synonyms DAHK
Species
Source
CAS No. 111543-77-2
MDL No. MFCD00237815
Sequence H-Asp-Ala-His-Lys-OH
Molecular weight 469.50
Molecular formula C₁₉H₃₁N₇O₇
Storage conditions –20 ± 5 °C

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