Anti-BAD Rabbit Polyclonal Antibody

Supplier: Thermo Scientific
PA512553
CAPIPA5-12553EA 3258.01 CAD
CAPIPA5-12553
Anti-BAD Rabbit Polyclonal Antibody
Antibodies
This antibody is predicted to react with mouse and rat based on sequence homology. Bad is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin are found to be involved in the regulation of this protein. Bad is phosphorylated on one or more of Ser-More Product Information
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SPECIFICATIONS

Antigen symbol BAD
Antigen name BCL2-associated agonist of cell death
Environmentally Preferable
Antigen synonyms BCL2L8|Bcl-2-binding component 6|BBC6|Bcl2 antagonist of cell death|BBC2|BAD
Antibody type Primary
Clonality Polyclonal
Conjugation Unconjugated
Reactivity Human
Host Rabbit
Isotype IgG
Western blot Yes
ELISA Yes
ImmunoChemistry Yes
ImmunoPrecipitation Yes
ImmunoFluorescence Yes
Gel shift Yes
Flow cytometry Yes
ChIP Yes
Neutralisation Yes
Modification phospho-Ser99
Immunogen KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S99 of human Bad
Form Liquid
Molecular weight 18.39 kDa
Purification Antigen affinity chromatography
Concentration Lot-specific
Cross adsorption No
Storage buffer PBS with 0.09% Sodium azide
Storage temperature Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at –20 °C
Tested applications Dot Blot

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