Anti-BTLA Rat Monoclonal Antibody [clone: 6F4]

Supplier: Prosci
36-160
75793-100EA 1148.9 CAD
75793-100
Anti-BTLA Rat Monoclonal Antibody [clone: 6F4]
Antibodies
B and T lymphocyte associated (BTLA) is an Ig domain superfamily protein with cytoplasmic immunoreceptor tyrosine-based inhibitory motifs. The herpes virus entry mediator (HVEM), a member of the TNF receptor (TNFR) superfamily, can act as a molecular switch that modulates T cell activation by propagating positive signals from the TNF-related ligand LIGHT (TNFR superfamily 14), or inhibitory signals through the Ig superfamily member BTLA. The binding site on HVEM for BTLA is conserved in the orphan TNF receptor UL144, present in human CMV. UL144 binds BTLA, but not LIGHT, and inhibits T cellMore Product Information
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