Salmonella typhimurium (strain LT2/SGSC1412/ATCC 700720) Recombinant Tryptophan synthase (from E. coli)

Supplier: Prosci

92-668
75791-898EA 1470.52 CAD
75791-898
Salmonella typhimurium (strain LT2/SGSC1412/ATCC 700720) Recombinant Tryptophan synthase (from E. coli)
Enzymes

Tryptophan synthase is a multienzyme alpha2 beta 2 complex composed of two protein subunit


This recombinant protein can be used for biological assays. For research use only.


Fusion-Tag: N-6 His tag


Tryptophan synthase catalyzes the last two steps in the synthesis of L-tryptophan (L-Trp). The alpha-subunit catalyzes cleavage of 3-indole-d-glycerol 3′-phosphate (IGP) to give indole and D-glyceraldehyde 3′-phosphate (G3P). Indole is then transferred through a 25-Å hydrophobic tunnel to the beta -subunit. The beta 2 subunit contains pyridoxal 5'-phosphate and catalyzes several pyridoxal 5'-phosphate-dependent reactions, including/3-elimination reactions 6 and a thiol-dependent transamination reaction. This enzyme is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from Animalia. As humans do not have tryptophan synthase, this enzyme has been explored as a potential drug target.

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