Human Recombinant Argininosuccinate Synthase (from E. coli)

Supplier: Prosci

91-986
75790-608EA 1525.33 CAD
75790-608
Human Recombinant Argininosuccinate Synthase (from E. coli)
Enzymes

Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits


This recombinant protein can be used for biological assays. For research use only.


Fusion-Tag: N-6 His tag


ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullinemia (CTLN1), an autosomal recessive disease which is characterized by severe vomiting spells and mental retardation.

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