Anti-CD86 Rat Monoclonal Antibody [clone: GL-1 (GL1)]

Supplier: Prosci
76-598
10764-704EA 549.11 CAD
10764-704
Anti-CD86 Rat Monoclonal Antibody [clone: GL-1 (GL1)]
Antibodies
The GL-1 monoclonal antibody reacts specifically with the mouse B7-2 (also known as CD86), a costimulatory molecule expressed by B and T lymphocytes, macrophages (thioglycollate-induced from peritoneum), astrocytes and dendritic cells. The memory CD4+ T lymphocytes express CD86 (as mRNA and protein). CD86, and the B7-1 (CD 80) molecule, are ligands for CD152 and CD28, and influence the costimulatory interactions between lymphocytes B and T. B7-2 is also involved in the mouse natural killer cell-mediated cytotoxicity. The GL-1 antibody blocks the mixed lymphocyte reaction (MLR) and inhibitsMore Product Information
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