Anti-INSR Rabbit Polyclonal Antibody (Cy5.5®)

Supplier: Bioss

BS-3492R-CY5.5
10369-790EA 1300.8 CAD
10369-790
Anti-INSR Rabbit Polyclonal Antibody (Cy5.5®)
Antibodies
Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated proteins serve as docking proteins for other signaling proteins that contain Src-homology-2 domains (SH2 domain) that specifically recognize different phosphotyrosines residues, including the p85 regulatory subunit of PI3K and SHP2. Phosphorylation of IRSs proteins lead to the activation of two mainMore Product Information
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