Anti-ARAF Rabbit Polyclonal Antibody (Cy3®)

Supplier: Bioss

BS-3421R-CY3
10368-794EA 1300.8 CAD
10368-794
Anti-ARAF Rabbit Polyclonal Antibody (Cy3®)
Antibodies
The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 and B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF and B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates and activates MEK. A RAF is expressed at a very high concentration in urogenital and kidney tissues.

Recommended Dilutions: IF(IHC-P): 1:50-200

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SPECIFICATIONS

Antigen symbol ARAF
Antigen name A-Raf Proto-Oncogene, Serine/Threonine Kinase
Environmentally Preferable
Antigen synonyms RP1-230G1.1|ARAF1|RAFA1|PKS2|A-RAF
Antibody type Primary
Clonality Polyclonal
Conjugation Cy3®
Reactivity Human,Rat,Mouse
Host Rabbit
Gene ID 369
Isotype IgG
ImmunoChemistry Yes
Modification phospho-Tyr301/Tyr302
Form liquid
Purification Purified by Protein A
Concentration 1 μg/μl
Cross adsorption No
Storage buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature Store at 4°C for 12 months
Shipping temperature 4°C

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