Anti-AKT1S1 Rabbit Polyclonal Antibody

Supplier: Bioss

BS-3346R
10367-716EA 1041.85 CAD
10367-716
Anti-AKT1S1 Rabbit Polyclonal Antibody
Antibodies
Subunit of mTORC1, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators ofMore Product Information
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