Anti-BLNK Rabbit Polyclonal Antibody (Cy7®)

Supplier: Bioss

BS-3054R-CY7
10350-602EA 1300.77 CAD
10350-602
Anti-BLNK Rabbit Polyclonal Antibody (Cy7®)
Antibodies
Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinaseMore Product Information
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