Anti-ESR2 Rabbit Polyclonal Antibody (Cy7®)

Supplier: Bioss

BS-0116R-CY7
10231-704EA 1300.77 CAD
10231-704
Anti-ESR2 Rabbit Polyclonal Antibody (Cy7®)
Antibodies
Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.

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