Anti-TET2 Rabbit Polyclonal T4 Antibody

Supplier: Prosci
7731
10126-724EA 917.13 CAD
10126-724
Anti-TET2 Rabbit Polyclonal T4 Antibody
Antibodies
TET2, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. It is a candidate tumor suppressor gene reported to be mutated in approximately 14% of patients with JAK2V617F-positive myeloproliferative neoplasms (1), and can be mutated in other hematopoietic disorders such as myelodysplastic syndromes, acute myeloid leukemia, and chronic myelomonocytic leukemia (2). Analysis of the TET2 and JAK2 mutations in these neoplasms suggests that mutations in TET2 do not represent aMore Product Information
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SPECIFICATIONS

Antigen symbol TET2
Environmentally Preferable
Antigen name tet methylcytosine dioxygenase 2
Antigen synonyms TET2
Antibody type Primary
Clonality Polyclonal
Conjugation Unconjugated
Reactivity Human,Mouse
Host Rabbit
Gene ID Q6N021
Isotype IgG
Western blot Yes
ELISA Yes
Immunogen TET2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human TET2. The immunogen is located within amino acids 1550 - 1600 of TET2.
Form Liquid
Molecular weight Predicted: 220 kDa Observed: 220 kDa
Purification TET2 antibody is affinity chromatography purified via peptide column.
Concentration 1 mg/mL
Cross adsorption No
Storage buffer TET2 Antibody is supplied in PBS containing 0.02% sodium azide.
Storage temperature TET2 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year.
Shipping temperature 4 °C

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